Zeiss Elyra 7 Lattice SIM

The Elyra is a fast and flexible super-resolution microscope for live cell imaging beyond the diffraction limit


The Zeiss Elyra 7 is a super-resolution Lattice SIM system capable of high speed 3D live cell imaging at twice the resolution of conventional microscopy, vastly improving acquisition time over standard SIM. And for appropriate fixed samples, single molecule imaging allows resolution of objects as small as 20nm, all on the same instrument.

  • Lasers: 405nm, 488nm, 561nm and 642nm
  • Cameras: 2x PCO.EDGE 4.2 CLHS sCMOS
  • Resolution: 110nm lateral (Lattice SIM), 20nm lateral (STORM/PALM)

Additional capabilities:

  • TIRF
  • 3D single-molecule imaging


The Zeiss Elyra 7 is available through the MCFP's iLab Booking System for trained users. To discuss access and training please contact Paul Brannon or Darryl Johnson.

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Sample preparation

Sample preparation for Lattice SIM is similar to confocal microscopy, compatible with most commonly used dyes with no additional steps. For single molecule imaging (STORM/PALM), sample-specific protocols are often necessary. Please contact Paul Brannon or Darryl Johnson for details.

Additional resources

Zeiss product page