NanoSight Pro

The Malvern NanoSight Pro instrument provides an easy-to-use, reproducible platform for nanoparticle characterisation

The NanoSight Pro utilises Nanoparticle Tracking Analysis (NTA) to characterise nanoparticles from 10nm - 2000 nm in solution. This particle-by-particle methodology produces high resolution results for particle size distribution and concentration while visual validation gives users extra confidence in the data. As well as particle size and concentration, protein aggregation and viscosity can all be analysed while a fluorescence mode provides detection of labelled particles.

Specifications


Manufacturer: Malvern
Particle size: 10 - 2000 nm
Concentration: 106 - 109 particles per mL
Fluorescence detection
Laser: 488 nm (blue)
Temperature control: 5oC below ambient to 50oC
Camera: sCMOS

Access

The NanoSight is available through the MCFP's iLab Booking System for trained users. To discuss access and training please contact Darryl or Paul below.

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Sample preparation

Samples need to be diluted into the concentration range of 106 - 109 particles per mL

Additional resources

Darryl Johnson

Darryl Johnson

Academic Specialist - Cytometry

Darryl leads the Cytometry node of the MCFP with expertise in mass and flow cytometry, and confocal microscopy. He has a background in molecular biology, biochemistry and immunology, and can help you with experimental design, preparation, acquisition, and interpretation.

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Paul Brannon

Paul Brannon

Platform Support Officer - Advanced Fluorescence Imaging

Paul leads the Advanced Fluorescence Imaging node of the MCFP and can assist with super-resolution imaging of a wide range samples, including tissues, live cells, and nanoparticles.

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See Also