Skip to main content
  1. Materials Characterisation and Fabrication Platform
  2. MCFP Learning
  3. Scanning Electron Microscopy
  4. Applications of SEM
  • Scanning Electron Microscopy
  • Introduction
  • Applications of SEM
  • All Fundamentals of SEMThe sourceThe columnThe chamber and sample stageElectron interactions and detected signalsVacuum modes
  • All Getting good imagesSample preparationBeam conditionsChoosing the detectorFocussing and working distanceBrightness and contrastScan speedStigmatism
  • Get into the lab!

Applications of SEM

Applications of SEM

SEM is used broadly in many fields of research due to its versatility, and ability to magnify surfaces far beyond what optical microscopy can achieve. Browse some of the applications of SEM at the MCFP below.

  • SEM enables researchers to look at the shape, roughness, or texture of surfaces. This is valuable when mechanical engineers are investigating how surface roughness leads to increased drag on aircraft or water vessels, or for physicists trying to understand how light may scatter from a poorly polished optical component.

  • SEM can be very precise for measuring the dimensions of micro/nano-sized materials, such as electro-spun polymer fibres for water filtration, or nanoparticles used for catalysis.

  • With careful sample preparation, SEM is used to investigate how mixed and layered materials behave, like investigating the interface between a carbon fibre and matrix in a composite, where electrolytes travel in novel battery materials, or the thickness of coatings.

  • Provided tissues and cells are prepared appropriately, SEM can even investigate biological materials, studying how bacteria interact with novel antibiotics, how cells develop on nanostructured surfaces, and where soil contaminants end up in plants.

  • SEM is more than just imaging, it can tell you about the elemental composition of materials as well, a technique called SEM-EDS. Here we can investigate where elements are located on a surface and within a structure, and even identify materials, like pigments used in a piece of artwork for example.

What are the Benefits and Limitations of SEM?

Clearly SEM is a powerful technique in research, but it is important to weigh up the strengths against some of the limitations.

Benefits of SEM Limitations

Spatial resolution:

  • Light microscopes are typically limited to ~200 nm
  • Electron microscopes can achieve ~2 nm or better

Depth of field (focus):

  • Resolution in light microscopy is usually achieved via confocal methods resulting in very narrow depth of focus
  • SEM achieves high resolution while maintaining good depth of field

Specialised detection and analysis modes:

  • The SEM can perform microanalysis where we can identify the elements/composition in a sample
  • Multiple detectable signals mean we can achieve improved contrast for a broad range of samples

Samples must be vacuum compatible:

  • Cannot image wet samples
  • Samples must be dehydrated which can limit applicability or add unwanted processing steps

Samples should ideally be conductive:

  • Insulating/non-conductive samples can be challenging to image in SEM
  • Adds extra preparation steps

No colour!

  • We are used to seeing the world in colour
  • Comparing optical and EM images can be challenging

It is a surface-scanning technique, we cannot see through things

  • We may be used to preparing samples under coverslips or imaging through coatings

Next - Fundamentals of SEM

Back to MCFP Learning Home

Materials Characterisation and Fabrication Platform

  • Our Capabilities
    • Nanofabrication
    • Nanomaterials Characterisation
      • Atomic force microscopy
      • Anton Paar NHT3 Nanoindenter
      • DataPhysics optical contact angle
      • Hirox RH-2000 2D/3D microscope
      • Quorum Q150T Sputter Coater
    • Advanced Fluorescence Imaging
      • Zeiss Elyra 7 Lattice SIM
      • Nikon A1R+ Confocal Microscope (CLSM)
      • STORM (Stochastic optical reconstruction microscopy): Nikon N-STORM
      • Olympus IX71 Fluorescence Microscope
    • Cytometry and Particle Characterisation
      • Mass cytometry
      • Halo
      • NanoSight Pro
      • Apogee A-50 Microflow Cytometer
      • CytoFLEX Nano
      • Imaging Flow Cytometry
      • ICP-MS
      • Imaging ToF-ICP-MS
    • Electron and Ion Microscopy
      • Scanning electron microscopy (SEM)
      • Helium ion microscopy and dual-beam nanofabrication
      • Sample Preparation
    • X-Ray Characterisation
      • X-ray diffraction (XRD)
      • X-ray fluorescence (XRF)
    • Vibrational Spectroscopy
      • Confocal Raman Microspectroscopy
      • Fourier Transform Infrared Microscopy
    • Biological Optical Microscopy Platform (BOMP)
    • Ian Holmes Imaging Centre
    • Trace Analysis for Chemical, Earth and Environmental Sciences (TrACEES)
    • University of Melbourne Research Infrastructure
    • MCFP 2023 User Survey
  • Access Equipment
  • MCFP news and events
    • MCFP Image Competition
      • MCFP Image Competition
  • Our Expertise
    • Elena Taran
    • Anders Barlow
    • Paul Brannon
    • Darryl Johnson
    • Dan Smith
    • Raveen Wijesuriya
    • Tian Zheng
    • Ray Dagastine
    • George Franks
  • Services for Industry
  • MCFP Learning
    • Video Guides
      • LUMOS ATR-FTIR Guides
      • CytoFLEX Guides
      • NanoSight Guides
      • FlexSEM-EDS Guides
    • FlexSEM-EDS FAQs
  • Sustainability
    • Sustainability Framework
    • Sustainability on Campus
    • FEIT Sustainability
    • Green Impact
    • Sustainable ANFF
  • Publications
  • Current Students
  • Library
  • Staff

Acknowledgement of Country

We acknowledge Aboriginal and Torres Strait Islander people as the Traditional Owners of the unceded lands on which we work, learn and live. We pay respect to Elders past, present and future, and acknowledge the importance of Indigenous knowledge in the Academy.

Read about our Indigenous priorities

Site footer

  • About us
  • Careers at Melbourne
  • Safety and respect
  • Newsroom
  • Contact
  • Campus locations

Contact details

Phone 13 MELB (13 6352)
International +61 3 9035 5511

Address
The University of Melbourne
Grattan Street, Parkville
Victoria 3010
Australia

Connect with us

  • Emergency
  • Terms & privacy
  • Accessibility
  • Privacy
  • The University of Melbourne (Australian University): PRV12150
  • CRICOS number: 00116K
  • ABN: 84 002 705 224